Michael Jennings (Ben Affleck) is a brilliant computer engineer hired for top-secret projects. After each job, Jennings' short-term memory is erased so he cannot recount any project information. Emerging from his latest assignment, a three-year contract with an eight-figure paycheck given to him by his longtime friend (Aaron Eckhart), Jennings is jolted when he is told that during the end of his assignment, he agreed to forfeit all payment.
Jennings has no recourse - until he receives a mysterious envelope containing clues to his forgotten past. With the help of a beautiful scientist (Uma Thurman) he once loved but now cannot remember, Jennings races to solve the puzzle of his past . . . while a terrifying discovery waits in his future.